Toward a systematic approach to opioid rotation

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Toward a systematic approach to opioid rotation

Patients requiring chronic opioid therapy may not respond to or tolerate the first opioid prescribed to them, necessitating rotation to another opioid. They may also require dose increases for a number of reasons, including worsening disease and increased pain. Dose escalation to restore analgesia using the primary opioid may lead to increased adverse events. In these patients, rotation to a di...

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ژورنال

عنوان ژورنال: Journal of Pain Research

سال: 2014

ISSN: 1178-7090

DOI: 10.2147/jpr.s55782